Nowadays, almost everyone is smoking even teenagers and pregnant ladies. Although health authorities around the world know that tobacco products appeal to children, are highly addictive, and cause the premature death of one-third to one-half of all long-term users, but no strong government agency has regulatory authority over tobacco products.
What’s in a cigarette?
There are at least 4000 chemicals in a cigarette. The best-known of these is nicotine, but tar, carbon monoxide, nitrogen oxides, hydrogen cyanide, ammonia, and other toxic irritants such as acrolein and formaldehyde are also present.
Structure of nicotine, 3-(1-methyl-2-pyrrolidinyl) pyridine
Formation of 3-nitrotyrosine has been associated with many diseases, including those associated with inflammation in lung airways. 3-nitrotyrosine is generated within the lung after inhalation of tobacco smoke, which may result in inactivation of many enzymes, oxidative injury in the lung and subsequently leads to decreased lung function.
In addition, cigarette smoking also reduces exhaled nitric oxide, NO, which means cigarette smoke may inhibit NO production. The reduction in NO production by cigarette smoke might be responsible, for the increased risk of systemic and pulmonary vascular disease in cigarette smokers.
It’s time to quit!!
Smoking-related disease is snatching our beloved family members and friends away from us at an alarming rate. According to the World Health Organization, smoking related-diseases kill one in 10 adults globally, causing approximately four million deaths a year.
There are tons of harmful effects of cigarette smoking
• Heart disease and stroke
• Emphysema
• Cancer
• ulcers, digestive ailments and chronic upset stomach
• bad breathe, teeth brown and yellow
• Harmful effects on Bones and Joints
• Infertility on men and women
It’s time to quit people.
Say “NO” to cigarette.
Molecular formula of nicotine
Nicotine, an organic compound, with the formula C10H14N2, is a naturally occurring liquid alkaloid, highly addictive drug found naturally in the tobacco plant. Many public health authorities believe nicotine is responsible for promoting and maintaining an addiction to smoking through its effects on the central nervous system.
The nicotine in inhaled tobacco smoke moves from the lungs, into the bloodstream and travels directly to the brain in just few seconds. Once there, nicotine will then triggers a number of chemical reactions that create immediate feelings of pleasure for the smoker, but these sensations are short-lived, subsiding within minutes. As the nicotine level drops in the blood, smokers feel anxious and agitated. So, in order to relieve the discomforts, smokers light up another cigarette...and then another. This is so called nicotine addiction.
Nicotine initially causes a rapid release of adrenaline. If you've ever chased by a dog or rushed around the office trying to finish a project by your deadline, you may be familiar with adrenaline's effects:
• Rapid heartbeat
• Increased blood pressure
• Rapid, shallow breathing
Besides, cigarette smoke also contains high levels of carbon monoxide, CO.
Carbon monoxide is a colorless, odorless, flammable, and highly poisonous gas. This inorganic compound also known as a silent killer as it is impossible for a human to detect. The symptoms of carbon monoxide exposure are typically seemingly harmless, as a result, the detection of CO poisoning often comes too late.
In the smoker’s body, CO may replace oxygen in the bloodstream. As a result, the CO blocks the absorption of oxygen in the blood and prevents them from carrying oxygen throughout the body. Carbon monoxide, CO, binds to the hemoglobin forming carboxyhemoglobin COHb. The chemical equation:
CO + Hb --> COHb (carboxyhemoglobin)
Breathing low levels of carbon monoxide can cause chest pain, headaches and nausea. Over time, the lack of oxygen in the body, can damage the heart and increase the risk of getting heart attack.
Nicotine, an organic compound, with the formula C10H14N2, is a naturally occurring liquid alkaloid, highly addictive drug found naturally in the tobacco plant. Many public health authorities believe nicotine is responsible for promoting and maintaining an addiction to smoking through its effects on the central nervous system.
The nicotine in inhaled tobacco smoke moves from the lungs, into the bloodstream and travels directly to the brain in just few seconds. Once there, nicotine will then triggers a number of chemical reactions that create immediate feelings of pleasure for the smoker, but these sensations are short-lived, subsiding within minutes. As the nicotine level drops in the blood, smokers feel anxious and agitated. So, in order to relieve the discomforts, smokers light up another cigarette...and then another. This is so called nicotine addiction.
Nicotine initially causes a rapid release of adrenaline. If you've ever chased by a dog or rushed around the office trying to finish a project by your deadline, you may be familiar with adrenaline's effects:
• Rapid heartbeat
• Increased blood pressure
• Rapid, shallow breathing
Structure of carbon monoxide, CO
Besides, cigarette smoke also contains high levels of carbon monoxide, CO.
Carbon monoxide is a colorless, odorless, flammable, and highly poisonous gas. This inorganic compound also known as a silent killer as it is impossible for a human to detect. The symptoms of carbon monoxide exposure are typically seemingly harmless, as a result, the detection of CO poisoning often comes too late.
In the smoker’s body, CO may replace oxygen in the bloodstream. As a result, the CO blocks the absorption of oxygen in the blood and prevents them from carrying oxygen throughout the body. Carbon monoxide, CO, binds to the hemoglobin forming carboxyhemoglobin COHb. The chemical equation:
CO + Hb --> COHb (carboxyhemoglobin)
Breathing low levels of carbon monoxide can cause chest pain, headaches and nausea. Over time, the lack of oxygen in the body, can damage the heart and increase the risk of getting heart attack.
Structure of nitrogen oxides
Another important class of compounds in cigarette smoke is nitrogen oxides, which the primary form is nitric oxide (NO). Nitric oxide is a gas with a sharp, sweet smell, colorless to brown at room temperature with a strong, harsh odor. It becomes a reddish-brown gas at temperatures above 70 degrees F.
In the body, nitric oxide is involved in oxygen transport to the tissues, the transmission of nerve impulses, and other physiological activities. Nitric oxide itself is not necessarily toxic; however, the relatively high concentration of NO present in tobacco smoke may render it toxic.
In the present study, scientist found that nitrogen oxides may react with the amino acid tyrosine, producing “3-nitrotyrosine”.
Molecular formula of 3-nitrotyrosine
In the body, nitric oxide is involved in oxygen transport to the tissues, the transmission of nerve impulses, and other physiological activities. Nitric oxide itself is not necessarily toxic; however, the relatively high concentration of NO present in tobacco smoke may render it toxic.
In the present study, scientist found that nitrogen oxides may react with the amino acid tyrosine, producing “3-nitrotyrosine”.
Molecular formula of 3-nitrotyrosine
Formation of 3-nitrotyrosine has been associated with many diseases, including those associated with inflammation in lung airways. 3-nitrotyrosine is generated within the lung after inhalation of tobacco smoke, which may result in inactivation of many enzymes, oxidative injury in the lung and subsequently leads to decreased lung function.
In addition, cigarette smoking also reduces exhaled nitric oxide, NO, which means cigarette smoke may inhibit NO production. The reduction in NO production by cigarette smoke might be responsible, for the increased risk of systemic and pulmonary vascular disease in cigarette smokers.
It’s time to quit!!
Smoking-related disease is snatching our beloved family members and friends away from us at an alarming rate. According to the World Health Organization, smoking related-diseases kill one in 10 adults globally, causing approximately four million deaths a year.
There are tons of harmful effects of cigarette smoking
• Heart disease and stroke
• Emphysema
• Cancer
• ulcers, digestive ailments and chronic upset stomach
• bad breathe, teeth brown and yellow
• Harmful effects on Bones and Joints
• Infertility on men and women
It’s time to quit people.
Say “NO” to cigarette.
While smoking is commonly understood to be addictive, we believe if you want to quit, you can, if you have the motivation and the belief that you can do it!!
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